Aerobic exercise and MSRT also increased the PT and PTT (P<0.001). D-dimer, as the index of fibrinolysis, was significantly increased in all exercise groups compared to before exercise (P<0.01) and to the control group (P<0.05). There was a significant reduction in fibrinogen in all exercise groups compared to before exercise (P<0.01) and to the control group (P<0.05). Before and 30 minutes after exercise, blood samples were collected to evaluate fibrinogen (mg/dL), D-dimer (mg/dL), prothrombin time (PT), partial thromboplastin time (PTT) and platelet count (×103/µL). The duration for aerobic, resistance and concurrent exercises was 60 minutes, while it was only 30 minutes for MSRT. A single session of exercise was performed: the aerobic group used a cycle ergometer (60% heart rate maximum) for 40 minutes, the resistance group performed 3 movements for the upper extremities and 3 movements for the lower extremities with 60% of 1-repetition maximum (each movement in 2 sets of 8-10 repetitions), the concurrent group followed by a combination of aerobic and resistance protocols, and the MSRT group performed four trials of the 40-meter MSRT. The present study aimed to differentiate the acute effects of aerobic, resistance and concurrent exercises, and 40-meter maximal shuttle run test (MSRT) on coagulation and fibrinolysis in non-athletic healthy young men.įifty participants (aged 20-30 years old) were randomly divided into a control and four exercise groups: aerobic, resistance, concurrent, and MSRT (N.=10 each).
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